In a double-blind study, 57 women with lymphedema received either placebo or butcher's broom combined with the modified Marginal benefits were seen in a much smaller study using this combination. Similar results were seen in a 12-week, double-blind, placebo-controlled trial with 148 participants.Īnother 12-week, double-blind, placebo-controlled trial with 141 participants used a combination of butcher’s broom extract and the bioflavonoid trimethylhesperidin chalcone, and found benefits. The results showed that leg swelling (the primary measurement used) decreased significantly in the butcher’s broom group as compared to the placebo group. Trial evaluated the effectiveness of a standardized butcher’s broom extract in 166 women with chronic venous insufficiency.įor a period of 12 weeks, participants received either placebo or butcher’s broom (one tablet twice daily containing 36.0 to 37.5 mg of a methanol dry extract concentrated at 15-20:1). What is the Scientific Evidence for Butcher’s Broom? One study suggests that butcher's broom may be helpful for this condition as well. Various treatments used for venous insufficiency have also shown promise for treating arm swelling (lymphedema) following No substantial studies have evaluated butcher’s broom for hemorrhoids, but because hemorrhoids are similar to varicose veins, it is a reasonable supposition that butcher’s broom might be helpful. However, several studies performed subsequently now provide preliminary supporting evidence for its use in chronic venous insufficiency. This recommendation was in place before any meaningful studies had been performed evaluating butcher’s broom for either of these purposes. Commission E also recommends butcher’s broom for the treatment of Venous insufficiency, a condition closely related to varicose veins, involves pain, swelling and fatigue in the calves. 20 Butcher’s broom acts most strongly when circulation is impaired, but some researchers caution that it is less effective when the disease has compromised venous wall receptor activity.]]> What Is Butcher's Broom Used for Today?īutcher's broom has been approved by Germany's Commission E as supportive therapy for In one large multicenter trial, 81.6% of treating physicians rated its efficacy as excellent, and the remaining physicians rated it as good. 16 – 24 All but two were randomized double-blind trials. Nine of these studies are summarized in Table 119-1. Although data quality varied, Cyclo 3 Fort significantly reduced CVI symptoms compared with placebo. The review included information on 10,246 subjects. 1 A meta-analysis evaluated 20 placebo-controlled, double-blind studies and 5 randomized trials against a comparator drug along with 6 single-arm studies without a placebo. Both animal and clinical studies support its effectiveness in CVI, and the German Commission E approved butcher’s broom as an adjunct treatment for this condition. There are no studies indicating whether butcher’s broom alone would achieve the same results.īutcher’s broom is most commonly used to alleviate the symptoms of CVI, including ankle edema, itching, tension, and cramping of the legs. (sweet clover) in some topical preparations. All discussions of butcher’s broom trials in the following therefore include the possibility that it was not butcher’s broom by itself that was active.īutcher’s broom is also paired with Melilotus spp. However, other studies indicated that the combination may have a synergistic effect. Butcher’s broom has action independent of the other compounds in the formula, and some studies indicated that butcher’s broom used alone may have a stronger effect. These formulas combine butcher’s broom with trimethylhesperidin chalcone (a flavonoid precursor) and ascorbic acid. Instead, most of the clinical studies investigated a proprietary combination formula known as Cyclo 3 Fort by Pierre Fabre Medicament of Paris, France, or Phlebodril by Pierre Fabre Pharma GmbH of Freiburg, Germany. There are few clinical studies on the effect of butcher’s broom alone.
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